There is a patent demand in the pharmaceutical, cosmetic and chemical industry for new alternative testing in order to assess the acute toxicity of new drugs, cosmetic ingredients or industrial chemical products that have to be in contact with humans or the natural environment.
The aim is to reduce the time for and cost of studies for the development of new active elements and reduce the number of experimental animals. Equally, these tests enable direct work on human cell lines instead of on animals, in order to study the toxicity of the liver or kidney, amongst other organs.
To this end, the validation of this new in vitro work methodology, compared to the conventional in vivo one is urgently needed, not only by corporate industry but also by the European Directives themselves. Both REACH (the UE regulating body for chemical products) and the 7th amendment to the Directive on cosmetics propose the replacement in, the short term, of animal experimentation. Currently, while a number of animal testing procedures for toxicity have been successfully substituted by alternative methods, systemic toxicities require new strategic tests to reach a suitable level of safety for the consumer.
Jose Maria Goenaga | Basque research
Warming ponds could accelerate climate change
21.02.2017 | University of Exeter
An alternative to opioids? Compound from marine snail is potent pain reliever
21.02.2017 | University of Utah
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
21.02.2017 | Earth Sciences
21.02.2017 | Medical Engineering
21.02.2017 | Trade Fair News