An amazingly sensitive method for selective analysis of amino acids, sugars, fatty acids, and other vital compounds has been developed by Russian scientists. This method allows determining even their trace quantities (fractions of nanograms). It is applicable in identifying cancerous cells and diagnostics of cancer at the earliest stage, when traditional diagnostics fail to catch sight of the disease.
Dr. Igor Revel’sky and his colleagues from the Moscow State University have developed method that provides a 100-times increased sensitivity of detecting amino acids and other vital compounds, i.e., a highest precision of their detection. This can be used in controlling the quality of drugs and foods and, prospectively, may become an effective technique of cancer diagnostics that will be more reliable than traditional histology.
The Russian scientists propose to begin with the separation of a complex mixture (e.g., the contents of a cell suspected of cancer). They separate firstly water-soluble substances from the rest of the mixture and, then, treat each of the two obtained fractions with specific reagents. As a result, the analyzed substances become volatile and separable with the use of a gas chromatograph, in which they are diffused along with a carrier gas through a liquid or solid adsorbent for differential adsorption. Each component produces its own peak in chromatogram.
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