New findings explaining the complicated process by which the "energy substations" of human cells split apart and recombine may lay the groundwork for new treatment approaches to a wide range of diseases, including some cancers and neurodegenerative diseases such as Parkinsons and Alzheimers.
Researchers from The Johns Hopkins Universitys Integrated Imaging Center; the University of California, Davis; and the California Institute of Technology collaborated on two new studies analyzing the mechanisms and proteins that underlie the fission-fusion cycle of the cellular powerplants, called mitochondria. Their findings were published in two recent issues of the journal Science.
"To understand the role that mitochondria play in both normal and aberrant cell biology, it is essential to first understand the fusion-fission process that occurs continuously in normal, healthy cells," said J. Michael McCaffery, a research scientist in the Johns Hopkins Department of Biology, director of the Integrated Imaging Center, and an author on both studies.
Lisa DeNike | EurekAlert!
Single-stranded DNA and RNA origami go live
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New antbird species discovered in Peru by LSU ornithologists
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DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
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