The unique connectivity pattern of a brain region determines the type of information available to it, and hence influences its function. Defining these patterns enhances our knowledge of human brain architecture and function. Non-invasive in vivo definition of brain connectivity patterns complements functional imaging and provides new understanding of disorders associated with developmental or regional alterations of brain connectivity. There are extensions to this approach to clinically important issues. As an example, brain connectivity problems are important in developmental and acquired brain disorders.
Researchers working within the University of Oxford Clinical Neurology Department have developed a technique that is able to provide non-invasive identification of boundaries between major nuclei in a patient undergoing surgery, thereby improving both targeting accuracy and outcomes. The invention relates to mapping the connectivity of the brain’s nervous system in a human, and uses imaging data derived from magnetic resonance imaging. New computer methods derive the anatomical connectivity patterns, and analyse the structure of the nervous system.
Testing the hypothesis that changes in fronto-thalamic circuitry i.e. thalamic dysfunction is a factor in schizophrenia becomes a reality using this methodology. Impairments in cortico-cortical connectivity are found in individuals with learning disabilities. The new method allows a quantitative approach to the differences so that actual variations in learning abilities and performance can be determined. At present localisation in stereotactic neurosurgery or deep brain stimulation of specific thalamic nuclei in movement disorders remains difficult. This approach to grey matter segmentation has the potential to improve targeting accuracy and outcomes.
Kim Bruty | alfa
New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg
Stingless bees have their nests protected by soldiers
24.02.2017 | Johannes Gutenberg-Universität Mainz
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
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The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
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Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
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