The unique connectivity pattern of a brain region determines the type of information available to it, and hence influences its function. Defining these patterns enhances our knowledge of human brain architecture and function. Non-invasive in vivo definition of brain connectivity patterns complements functional imaging and provides new understanding of disorders associated with developmental or regional alterations of brain connectivity. There are extensions to this approach to clinically important issues. As an example, brain connectivity problems are important in developmental and acquired brain disorders.
Researchers working within the University of Oxford Clinical Neurology Department have developed a technique that is able to provide non-invasive identification of boundaries between major nuclei in a patient undergoing surgery, thereby improving both targeting accuracy and outcomes. The invention relates to mapping the connectivity of the brain’s nervous system in a human, and uses imaging data derived from magnetic resonance imaging. New computer methods derive the anatomical connectivity patterns, and analyse the structure of the nervous system.
Testing the hypothesis that changes in fronto-thalamic circuitry i.e. thalamic dysfunction is a factor in schizophrenia becomes a reality using this methodology. Impairments in cortico-cortical connectivity are found in individuals with learning disabilities. The new method allows a quantitative approach to the differences so that actual variations in learning abilities and performance can be determined. At present localisation in stereotactic neurosurgery or deep brain stimulation of specific thalamic nuclei in movement disorders remains difficult. This approach to grey matter segmentation has the potential to improve targeting accuracy and outcomes.
Kim Bruty | alfa
Scientists spin artificial silk from whey protein
24.01.2017 | Deutsches Elektronen-Synchrotron DESY
Choreographing the microRNA-target dance
24.01.2017 | UT Southwestern Medical Center
A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
24.01.2017 | Physics and Astronomy
24.01.2017 | Life Sciences
24.01.2017 | Health and Medicine