Painful and damaging chemotherapy may one day be a thing of the past. Researchers at the Georgia Institute of Technology and Purdue University have developed nano-sized particles that can target and trick cancer cells into absorbing them. Once inside, the particles may soon be able to deliver a pharmaceutical payload, killing the tumor from within, avoiding the destruction of healthy cells responsible for much of the damage caused by traditional chemotherapy. The research is published in the August 25 edition of the Journal of the American Chemical Society.
"We’ve developed a class of particles called core/shell nanogels that we can functionalize with a specific kind of chemistry that allows them to target cancer cells,” said L. Andrew Lyon, associate professor at Georgia Tech’s School of Chemistry and Biochemistry.
That specific kind of chemistry is folic acid. Cancer cells have more receptors for folic acid and absorb more of the nutrient than healthy cells. In a process akin to hiding a dog’s heartworm pill in a glob of peanut butter, researchers covered the surface of the nanogels with folic acid, disguising the particles as an essential nutrient. Once the cancer cells took the particles in, researchers increased the temperature of the cells, causing the particles to clump together and shrink, killing the cell.
David Terraso | EurekAlert!
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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