VeraChem LLC founders Drs. Michael Gilson, Michael Potter, and Hillary Gilson, using UMBI licensed intellectual property, are creating scientific software that provides expert users with tools for computer-aided drug discovery and molecular design. VeraChem’s recent first sale, a pre-release version of Vconf, is followed by the projected launch on September 8 of Vcharge, a new software product for computing molecular properties important in drug design. The official launch of Vconf is expected to follow later in 2004.
“Vcharge combines speed and accuracy in a unique software package that will be available for the Linux and Windows operating systems,” says Dr. Gilson, Chief Scientific Officer for VeraChem LLC and Professor at UMBI’s Center for Advanced Research in Biotechnology. “This product is just the first in a series that will bring advanced computational methods in an affordable and user-friendly format to experts in the pharmaceutical and biotechnology industries.”
“Vcharge is a tool for computer-aided drug design,” says Dr. Gilson. “It allows the designer to compute the atomic charges of a candidate drug molecule as a step in determining whether it will effectively bind a targeted protein. Most drugs work by binding tightly to a targeted protein molecule. For example, HIV protease inhibitors help patients by binding and blocking the function of a protein that the AIDS virus needs to survive and reproduce. Each atom of a protein carries a small electrical charge and, since opposite charges attract while like charges repel, it is important that the atoms of a drug molecule have charges which complement the targeted protein.”
Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH
Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences