Columbia University Medical Center and Albert Einstein College of Medicine researchers have identified a possible cause of an inherited form of Parkinson’s disease, which may be related to more common forms of the disease. The findings are reported in the August 27, 2004 issue of Science.
While the cause of most cases of Parkinson’s disease is unknown, a few cases are inherited and can be traced to mutations in four different genes, including the alpha-synuclein gene. This is the first study that may pinpoint the mechanism by which the mutant gene initiates a cascade of events that causes this devastating neurological disease.
"This discovery could aid in the development of new, targeted treatments to slow or stop the disease progression," said David Sulzer, Ph.D., professor of neurology and psychiatry at Columbia University College of Physicians and Surgeons and senior author of the study. "This is an extension of the genetic research that discovered the mutant alpha-synuclein gene and it is exciting to see how this information can be used to possibly determine the cause of Parkinson’s disease."
Elizabeth Streich | EurekAlert!
Flow of cerebrospinal fluid regulates neural stem cell division
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Chemists at FAU successfully demonstrate imine hydrogenation with inexpensive main group metal
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So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
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