A stroke leaves a permanent gap in the brain that can destroy a persons ability to speak and move normally. Filling that gap with new cells has been a long sought-after goal of stem cell research, but all attempts have met with complications - until now. Researchers at Stanford University School of Medicine report the first success using stem cells to populate the damaged region with new neurons in rats. If those cells also replace the function of the lost cells, they could help people recover after a stroke.
In the study, published in the July 26 advance online issue of Proceedings of the National Academies of Science, neurosurgeon Gary Steinberg, MD, PhD, and his group found that fetal stem cells injected into the brains of rats could migrate to the right location and turn into the appropriate types of neurons. "Were not saying we can treat patients immediately, but its a big step forward. This gives us considerable optimism for these cells," Steinberg said.
The cells in question are at an early stage of developing into the mature brain and are still able to form many types of brain cells, but until now the cells have shown that potential only in a lab dish. Stem Cells Inc., a company founded by study co-author and pathology professor Irving Weissman, MD, reported isolating these cells from human fetal tissue in December 2000. The company now grows the cells in bulk and distributes them to researchers studying spinal cord injuries as well as Parkinsons, Alzheimers and other brain disorders. Steinbergs is the first paper to show that the cells can transform into the appropriate cell types in an animal.
Amy Adams | EurekAlert!
'Lipid asymmetry' plays key role in activating immune cells
20.02.2018 | Biophysical Society
New printing technique uses cells and molecules to recreate biological structures
20.02.2018 | Queen Mary University of London
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
20.02.2018 | Life Sciences
20.02.2018 | Medical Engineering
20.02.2018 | Physics and Astronomy