Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Novel Stem Cell in Blood and Vessel Formation Identified

26.07.2004


A research study published this week has for the first time identified the specific precursor stem cell that gives rise not only to the important cells lining our blood vessels but also the blood itself.



Dr. Mick Bhatia and his colleagues at Robarts Research Institute in London, Ontario, had demonstrated last year that human embryonic stem cells (hESCs) can make blood cells; and they and others have known for some time that there is a connection between the development of the blood and the formation of the vessels it flows through. Now, Dr. Bhatia has traced the development of these interrelated systems back to a specific population of primitive endothelial-like cells in the lining of the earliest blood vessels. His findings are published in this week’s edition of the journal Immunity.

Understanding this common lineage of blood and cells comprising veins and arteries provides a powerful tool to test ideas about how these human precursor cells could potentially be transplanted to repair damaged tissue or organs, such as in cases of trauma or injury where vessels have been torn and major blood loss has occurred, or in cancer to “turn off” the formation of blood vessels that feed a growing tumour.


“We think we’ve identified a version of human blood precursors that may be the most potent of blood cells -- the one that has the greatest developmental potential to promote repair of vessels as well as regeneration of the blood itself,” explained Dr. Bhatia, Director of the Krembil Centre for Stem Cell Biology at Robarts. “This precursor cell provides an important new tool in our biological toolkit that can help us understand precisely how stem cells give rise to the tissues and organs of the body -- and how we can harness that potential to minimize the damage of injury and disease.”

Still, Dr. Bhatia, who is also an associate professor of microbiology and immunology at The University of Western Ontario, stresses that much fundamental biology remains in stem cell research.

Before new therapies can be developed, tested and safely used in humans, researchers continue to refine methods in identifying, purifying and verifying rare and elusive stem cells for study. They are also identifying what genes are important in the development and differentiation of these cells, what genes are linked to blood cancers, such as leukemias, and which particular growth factors can have a stimulating -- or inhibiting -- effect on stem cell development.

| newswise
Further information:
http://www.robarts.ca

More articles from Life Sciences:

nachricht Zap! Graphene is bad news for bacteria
23.05.2017 | Rice University

nachricht Discovery of an alga's 'dictionary of genes' could lead to advances in biofuels, medicine
23.05.2017 | University of California - Los Angeles

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

Im Focus: Bacteria harness the lotus effect to protect themselves

Biofilms: Researchers find the causes of water-repelling properties

Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

Innovation 4.0: Shaping a humane fourth industrial revolution

17.05.2017 | Event News

 
Latest News

Scientists propose synestia, a new type of planetary object

23.05.2017 | Physics and Astronomy

Zap! Graphene is bad news for bacteria

23.05.2017 | Life Sciences

Medical gamma-ray camera is now palm-sized

23.05.2017 | Medical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>