A University of California scientist working at Los Alamos National Laboratory with collaborators from the University of Cambridge (England) and the World Health Organization National Influenza Center at Erasmus Medical Center, (Rotterdam, Netherlands) have developed a computer modeling method for mapping the evolution of the influenza virus. The method could soon help medical researchers worldwide develop a better understanding of certain mutations in influenza and other viruses that allow diseases to dodge the human immune system.
In a paper published in todays edition of the journal Science, the team of scientists from the United States and Europe describe their work quantifying and visualizing the antigenic and genetic evolution of the influenza A (H3N2) virus from its initial introduction into humans in 1968 up to 2003. The study resulted in a map that shows the virus evolved as a series of 11 closely related virus clusters as it has sought to elude human immunity over the decades.
The mapping method will allow researchers involved in vaccine development and viral surveillance programs for influenza, and potentially for other pathogens such as Hepatitis C and HIV as well, to quantify and visualize the evolution of these viruses. It can assist in monitoring antigenic differences among vaccine and circulating viral strains, and can help in quantifying the effects of vaccination. The approach also offers a route for predicting the relative infection success of emerging virus strains.
Todd Hanson | EurekAlert!
Water forms 'spine of hydration' around DNA, group finds
26.05.2017 | Cornell University
How herpesviruses win the footrace against the immune system
26.05.2017 | Helmholtz-Zentrum für Infektionsforschung
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy