Researchers from the Universitat Autònoma de Barcelona have developed the first international server that allows the user to analyze genetic diversity on a large scale. The web service, published in the special edition of Nucleic Acids Research on bioinformatics, will facilitate research about the genetic basis of hereditary diseases. The server is called PDA (Pipeline Diversity Analysis) and for the first time biologists around the world can search for small variations in the genomes of different individuals and different species using the data stored in large public genome databases, such as Genbank.
These variations are the key to understanding the great diversity in living beings on earth, as well as the large diversity that exists in individuals from the same species. In the case of our own species, these differences determine whether a person has blue or brown eyes, fair or dark skin, or a higher or lower risk of getting a certain type of cancer. This is why genetic variability, as well as being a key element in evolutionary biology and in biology in general, provides very valuable information for studying illnesses with a genetic origin, and it has become one of the main scientific research areas in the genomic field.
The web service, published this July in the special edition of the journal Nucleic Acids Research, consists of a set of programs that automatically search for genetic sequences in large public DNA databases. The sequences are grouped and the genetic diversity is measured in different regions, searching for what scientists call nucleotide polymorphisms. These are small variations in the “letters” of the DNA molecule that hold the genetic information of different individuals of a species.
Octavi López Coronado | alfa
Link Discovered between Immune System, Brain Structure and Memory
26.04.2017 | Universität Basel
Researchers develop eco-friendly, 4-in-1 catalyst
25.04.2017 | Brown University
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
26.04.2017 | Life Sciences
26.04.2017 | Physics and Astronomy
26.04.2017 | Earth Sciences