Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

UAB creates the first Internet server to search for genetic diversity

19.07.2004


Researchers from the Universitat Autònoma de Barcelona have developed the first international server that allows the user to analyze genetic diversity on a large scale. The web service, published in the special edition of Nucleic Acids Research on bioinformatics, will facilitate research about the genetic basis of hereditary diseases. The server is called PDA (Pipeline Diversity Analysis) and for the first time biologists around the world can search for small variations in the genomes of different individuals and different species using the data stored in large public genome databases, such as Genbank.

These variations are the key to understanding the great diversity in living beings on earth, as well as the large diversity that exists in individuals from the same species. In the case of our own species, these differences determine whether a person has blue or brown eyes, fair or dark skin, or a higher or lower risk of getting a certain type of cancer. This is why genetic variability, as well as being a key element in evolutionary biology and in biology in general, provides very valuable information for studying illnesses with a genetic origin, and it has become one of the main scientific research areas in the genomic field.

The web service, published this July in the special edition of the journal Nucleic Acids Research, consists of a set of programs that automatically search for genetic sequences in large public DNA databases. The sequences are grouped and the genetic diversity is measured in different regions, searching for what scientists call nucleotide polymorphisms. These are small variations in the “letters” of the DNA molecule that hold the genetic information of different individuals of a species.



The creation of bioinformatic tools that can automate the process of searching for and analyzing data is now one of the priorities of biomedical research in order to deal with the avalanche of molecular data that is generated world-wide. The server PDA is available for use for the scientific community at the Internet address http://pda.uab.es

Octavi López Coronado | alfa
Further information:
http://www.uab.es

More articles from Life Sciences:

nachricht Making fuel out of thick air
08.12.2017 | DOE/Argonne National Laboratory

nachricht ‘Spying’ on the hidden geometry of complex networks through machine intelligence
08.12.2017 | Technische Universität Dresden

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

Im Focus: Virtual Reality for Bacteria

An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications

Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...

Im Focus: A space-time sensor for light-matter interactions

Physicists in the Laboratory for Attosecond Physics (run jointly by LMU Munich and the Max Planck Institute for Quantum Optics) have developed an attosecond electron microscope that allows them to visualize the dispersion of light in time and space, and observe the motions of electrons in atoms.

The most basic of all physical interactions in nature is that between light and matter. This interaction takes place in attosecond times (i.e. billionths of a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Midwife and signpost for photons

11.12.2017 | Physics and Astronomy

How do megacities impact coastal seas? Searching for evidence in Chinese marginal seas

11.12.2017 | Earth Sciences

PhoxTroT: Optical Interconnect Technologies Revolutionized Data Centers and HPC Systems

11.12.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>