EMBL and partners begin MitoCheck, a multinational research project on cell cycle regulation
Scientists at the European Molecular Biology Laboratory (EMBL) join forces with top scientists from eleven research institutes in Austria, Germany, Italy, France and the United Kingdom for "MitoCheck" - the largest integrated research project on cell cycle control within the European Commission’s 6th Framework Programme (FP6). The partners will receive an 8.5 million Euro grant to address a fundamental question: How is cell division regulated?
Cell division (or "mitosis") is one of the key processes of life. Mistakes during mitosis can cause infertility and mental retardation, and can contribute to cancer. For the most part, mitosis is still poorly understood. Scientists do know that protein kinases - a certain type of enzyme - play a key role, but researchers don’t know how these enzymes bring about the important changes in cells that cause them to divide. To understand cell division in a comprehensive manner, the MitoCheck consortium of European scientists will systematically hunt for all genes that are required for division and then check the products of these genes to see how they are regulated by mitotic kinases.
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