Robert Hoffmann and Alfonso Valencia of the Spanish National Centre of Biotechnology (CNB/CSIC) in Madrid have developed a new web-based tool called iHOP (Information Hyperlinked over Proteins) to help researchers explore scientific literature and integrate information in a more controlled and targeted manner.
Reporting in the Nature Genetics journal (Nature Genetics 36, 664, 01 Jul 2004), the two scientists describe how iHOP, which was developed as part of the EU-funded ORIEL and TEMBLOR projects, converts the 14 million abstracts in the PubMed (National Library of Medicine) bibliographic database into a network of interlinked references to genes, proteins, mutations, diseases and (bio)chemical compounds. By using genes and proteins as hyperlinks between sentences and articles, iHOP makes the information stored in PubMed accessible as one navigable resource.
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