Live skin substitute to unlock new products
Many long-established skin products, such as shampoos and soaps, contain harmful or ineffective ingredients because effective testing methods were unavailable when they were developed.
The first ever model of live skin with a full ecosystem of micro-organisms – created at the University of Leeds – has the potential to help develop dozens of new products and change the ingredients of many household names.
Skin Research Centre director Dr Richard Bojar said the new tests would unlock product development which stalled as long as 40 years ago.
“Many microbial compounds used in products for acne, eczema, dandruff, and so on are very old,” he said. “Manufacturers were not able to test them accurately when they were created and now they are facing very large investments to develop new ones.
“A colonised skin equivalent model will provide researchers with a valuable screening tool allowing them to shortcut the development process. This will lead to more innovation in product development and will enable many household names to reformulate their products using modern ingredients.”
Skin equivalents have been used for some time and colonisation by single microbial species has been achieved, but the accurate modelling of a full skin ecosystem is a first.
The best model for testing products for use on humans is human skin, using volunteers or patients, but this limits testing to products which have been thoroughly safety-tested. The new model will make innovation much cheaper.
Healthy human skin supports a substantial microbial community which helps to protect us from infection and is essential for good skin health. The structure of human skin is unique in the animal kingdom so no predictive animal models have ever been available.
Vanessa Bridge | alfa
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes
The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....
Larsen C Ice Shelf rift finally breaks through
A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...
Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision
Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...