Significant abnormalities observed in cloned mice help reinforce the need to continue to avoid the reproductive cloning of humans, a scientist said on Wednesday 30 June 2004 at the 20th annual conference of the European Society of Human Reproduction and Embryology. Dr. Takumi Takeuchi, from Cornell University, New York, USA told a media briefing that he and Dr. Gianpiero Palermos team had compared imprinting abnormalities (the process where specific genes inherited from both parents are silent) in mice embryos derived from assisted reproduction techniques and from cloning.
“We found significantly impaired development in the cloned embryos compared with those derived from more conventional ART techniques”, said Dr. Takeuchi, “and this has made us more convinced that reproductive cloning is unsafe and should not be applied to humans.”
Drs. Takeuchi and Palermo were prompted to undertake the research by concerns about the increased incidence of imprinting abnormalities in children born after ARTs. The most prominent of these is Beckwith-Wiedemann syndrome, where children are born larger than normal.
Emma Mason | alfa
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