If DNA can be compared to an architect who gets all the glory for designing the building, RNA can be compared to the engineer who often goes unrecognized, but is needed to turn the blueprints into a real three-dimensional, functional and safe structure. RNA has numerous functions in a cell, including translating the genetic blueprints found in DNA and catalyzing reactions in the cell to build proteins.
In order to carry out its functions, strands of RNA molecules will bind with other RNA molecules, making double-stranded RNA, or will bind with proteins, making RNA-protein complexes, or RNPs.
Wherever RNA occurs in the cell, ubiquitous RNA helicase enzymes are responsible for rearrangements of such complexes. RNA helicases are proteins that burn the universal cellular fuel molecule ATP and use the energy gained from this reaction to unwind double-stranded RNA. It has long been assumed that these enzymes, essential for all aspects of RNA metabolism, exclusively unwind double-stranded RNA.
George Stamatis | EurekAlert!
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