Because they target and track deadly brain tumor cells – even those that migrate within the brain – neural stem cells appear to be effective "delivery systems" to transport cancer-killing gene and immune products. But not all neural stem cells take on this tracking role.
Now researchers at Cedars-Sinais Maxine Dunitz Neurosurgical Institute, using mouse and human cells, have defined a subset of neural stem cells that have this tumor-tracking potential. They also have identified a biochemical mechanism that appears to govern the homing behavior. Their results appear in the May/June issue of the journal Neoplasia.
The prognosis for patients with malignant brain tumors called gliomas is extremely poor. Those with glioblastoma multiforme, the most aggressive of the gliomas, usually have a life expectancy of only months from the time of diagnosis. Survival for two years is extremely rare, even with aggressive treatment. Chemotherapy and radiation therapy have only minimal impact, and because gliomas have poorly defined borders, with glioma cells intermingling with healthy brain tissue, complete surgical removal is nearly impossible. Furthermore, cancer cells migrate away from the main tumor to form satellites that often escape treatment and lead to recurrence.
Sandra Van | Van Communications
Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München
Second research flight into zero gravity
21.10.2016 | Universität Zürich
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
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21.10.2016 | Materials Sciences