New Saint Louis University research sheds light on how obesity occurs
Saint Louis University researchers believe theyve won a major skirmish in the battle of the bulge, and their findings are published in the May issue of Diabetes.
"We figured out how obesity occurs," says William A. Banks, M.D., professor of geriatrics in the department of internal medicine and professor of pharmacological and physiological science at Saint Louis University School of Medicine. "The next step is coming up with the solution."
The scientists used mice to look at how leptin, a hormone secreted by fat cells that tells us to stop eating, gets into the brain. They found that in obese mice, high triglycerides, a type of fat in the bloodstream, prevents leptin from getting into the brain, where it can do its work in turning off feeding and burning calories.
Nancy Solomon | EurekAlert!
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