International consortium provides the first step towards a comprehensive functional link between the genome sequence scaffold and human diseases
The announcement of the human genome sequence three years ago was widely hailed as one of the great scientific achievements in modern history. But sequencing the genome is just a first step -- the monumental task of ascribing biological meaning to those sequences has just begun. The H-Invitational international consortium, led by Takashi Gojobori (Tokyo, Japan) has taken a significant step towards this goal, by validating and annotating over 20,000 human genes, using publicly available resources.
By relating intermediate gene products called messenger RNAs to each of their parent genes, and exhaustively connecting them to the relevant proteins, the consortium has established a reliable systematic network of human-curated relationships between genes and their biological functions.
Hemai Parthasarathy | EurekAlert!
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