A team of researchers from the University Hospital of Grenoble (CHU – Inserm U647) and the ESRF1 has found a new treatment that improves the survival of rats with high-grade gliomas.
This research was carried out at the ESRF Medical Beamline. It showed that after a year of this treatment, three rats out of 10 were considered cured, whereas without treatment, all would be dead. The results have just been published in the scientific journal Cancer Research. A glioma is one of the most frequent brain tumours in human adults, and it is not curable. Clinical trials on humans are planned for the near future.
Today, the median survival for patients with glioma is less than a year. Around 5 to 10 adults out of 100.000 suffer from this brain tumour. Traditional radiotherapy using hospital X-rays only has a palliative effect because gliomas are some of the most radio-resistant human tumours. Chemotherapy is ineffective most of the time. Several therapeutic techniques have been developed over the last years using animal models, but none has had such successful results as this new treatment with cis-platinum combined with monochromatic synchrotron x-rays. This new technique combines chemotherapy with radiotherapy in such a way that both techniques are effective when associated.
Montserrat Capellas | alfa
One step closer to reality
20.04.2018 | Max-Planck-Institut für Entwicklungsbiologie
The dark side of cichlid fish: from cannibal to caregiver
20.04.2018 | Veterinärmedizinische Universität Wien
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
20.04.2018 | Physics and Astronomy
20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy