Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Making noise about gene silencing

17.03.2004


Advances in an area widely regarded in scientific circles as the ’next big thing’ - RNA interference (RNAi) - will be the major focus of a CSIRO-hosted conference on the Gold Coast in September.



The chairman of the ’Horizons in Livestock Sciences’ conference, CSIRO’s Dr Tim Doran, says RNAi research has major implications for plant, animal and human health.

"Since RNAi was first described in the 1990s, the technology has been rapidly adopted in laboratories around the world," Dr Doran says. "RNAi can be applied to a range of research problems - the key areas being a way of controlling disease and a tool for gene identification."


Dr Doran says RNAi is a phenomenon by which double-stranded RNA promotes gene-specific silencing.

"Eukaryotic cells see double-stranded RNA as an unwanted invader, and trigger a mechanism to destroy it and the single-stranded RNA of the same sequence. Without the RNA, the gene products - the proteins - cannot be produced and the gene is effectively silenced," Dr Doran says.

A leading speaker is CSIRO Plant Industry’s Dr Peter Waterhouse. In 1995, the CSIRO team were first to demonstrate gene silencing in plants by intentionally using double-stranded RNA. Since the discovery of this mechanism, Dr Waterhouse and his team have focused on understanding the natural roles of gene silencing and exploiting it for genomics, virus protection and quality trait research.

Director of the Institute of Molecular Bioscience, Professor John Mattick (AO), will present the conference’s opening address. A leading figure in molecular biology and biotechnology, Professor Mattick’s key research interests include the role of non-coding RNA in the evolution and development of complex organisms.

International speakers include Chief Executive Officer/Chief Scientific Officer of the German-based company, Cenix BioScience, Dr Christophe Echeverri. In 2003, Dr Echeverri was listed in the world’s 100 Top Young Innovators by the Massachusetts Institute of Technology’s magazine Technology Review. This award recognised Dr Echeverri’s pioneering work in establishing the feasibility of systematic, high-throughput applications of RNAi, probing gene functions on a genome-wide scale.

Also speaking is the Chair of the Division of Molecular Biology at the Beckman Research Institute of the City of Hope, Los Angeles, and Dean of the Institute’s Graduate School of Biological Sciences, Dr John Rossi. Dr Rossi is regarded as a world leader in the development of therapeutic applications of RNAi and in HIV/AIDS clinical research and is a scientific advisor to Benitec Australia Ltd.

The DNA-directed RNAi (ddRNAi) field is one where holding intellectual property rights is a critical step to permit commercialisation. CSIRO and Benitec jointly hold the only issued US and UK patents for gene silencing in animals and have developed a substantial estate of intellectual property for supporting technologies. In December 2003, CSIRO, Benitec and the Queensland Department of Primary Industries announced a strategic agreement that provided clear pathways for the global commercialisation of this breakthrough technology. Benitec focuses on commercialising ddRNAi for ’human applications’ and CSIRO focuses on commercialising ’non-human applications’, including plants, animals and insects.

More information:

Dr Tim Doran, CSIRO Livestock Industries, +61 3 5227 5788
Email: timothy.doran@csiro.au
Dr Peter Waterhouse, CSIRO Plant Industry, + 61 2 6246 5365
Email: peter.waterhouse@csiro.au
Professor John Mattick, Institute of Molecular Bioscience, + 61 7 3346 2110
Email: j.mattick@imb.uq.edu.au
Dr Ken Reed, Director, Research and Technology, Benitec Australia, +61 7 3217 8540
Email: kreed@benitec.com
Dr John Rossi, Beckman Research Institute of the City of Hope
Email: JRossi@coh.org
Dr Christophe Echeverri, Cenix BioScience
Email : fuerst@cenix-bioscience.com

The conference program is available at: www.livestockhorizons.com

Media assistance:
Judith Maunders, CSIRO Livestock Industries, +61 3 5227 5426, mobile: 0409 031 658
Email: judith.maunders@csiro.au

Bill Stephens | CSIRO
Further information:
http://www.csiro.au/index.asp?type=mediaRelease&id=Prhorizons2
http://www.livestockhorizons.com

More articles from Life Sciences:

nachricht Link Discovered between Immune System, Brain Structure and Memory
26.04.2017 | Universität Basel

nachricht Researchers develop eco-friendly, 4-in-1 catalyst
25.04.2017 | Brown University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

Scientist invents way to trigger artificial photosynthesis to clean air

26.04.2017 | Materials Sciences

Ammonium nitrogen input increases the synthesis of anticarcinogenic compounds in broccoli

26.04.2017 | Agricultural and Forestry Science

SwRI-led team discovers lull in Mars' giant impact history

26.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>