Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Freeze-dried sperm can fertilize rabbit oocytes

04.03.2004


A team of reproductive biologists from the United States and Japan has succeeded in fertilizing rabbit oocytes with "dead" freeze-dried rabbit sperm. The fertilized eggs continued to develop into embryos, some of which were transplanted into female rabbits.



The researchers---from the University of Connecticut, the University of Hawaii, and Hirosaki University---note that rabbit sperm share many similarities with human sperm, so their results suggest that the freeze-drying technique could be used to preserve sperm from humans and many other animal species.

Previously, only freeze-dried sperm from mice had been shown to support embryo development. Mouse sperm, however, are significantly different from sperm of most other mammals because they do not contribute a cellular organelle known as a centrosome to the fertilized oocyte. The question remains whether the centrosomes in rabbit sperm survive the freeze-drying or whether centrosomes are not essential for embryos of mammals to develop.


Freeze-drying immobilizes rabbit sperm, breaks plasma membranes, and causes fragmentation of the sperm tails. Nonetheless, the chromosomes remain intact in the "dead" sperm. Even after being stored at temperatures above freezing for more than two years, the treated sperm were as capable as fresh sperm at fertilizing rabbit oocytes.

In a paper scheduled for publication in Biology of Reproduction, the team headed by Xiangzhong Yang of the Center for Regenerative Biology at the University of Connecticut, Storrs, and Ryuzo Yanagimachi of the University of Hawaii Medical School, Honolulu, reports that one rabbit pup was born after 230 oocytes fertilized with freeze-dried sperm were transferred to 8 female rabbits. The full-term pup appeared normal but was still-born, a common outcome of single-birth pregnancies in rabbits.

The researchers believe that improvements in their procedure will someday enable freeze-dried sperm of mammalian species to be stored indefinitely at room temperatures.


Biology of Reproduction, published by the Society for the Study of Reproduction, is the top-rated peer-reviewed journal in the field of reproductive biology.

Dr. Xiangzhong Yang | EurekAlert!
Further information:
http://www.ssr.org/

More articles from Life Sciences:

nachricht The birth of a new protein
20.10.2017 | University of Arizona

nachricht Building New Moss Factories
20.10.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>