Scientists have created an unlimited supply of a type of nerve cell found in the spinal cord – a self-renewing cell line that offers a limitless supply of human nerve cells in the laboratory. Such a supply has long been one goal of neurologists anxious to replace dead or dying cells with healthy ones in a host of neurological diseases.
In this study, appearing in the March issue of Nature Biotechnology, the scientists then used the cells to partially repair damaged spinal cords in laboratory animals, re-growing small sections of the spinal cord that had been damaged. Doctors emphasize that tests in people with damaged spinal cords or other neurological conditions are a long ways off.
The researchers, led by neurologist Steven Goldman, M.D., Ph.D., of the University of Rochester Medical Center, created the unique cells by introducing a gene called telomerase, which is responsible for the ability of stem cells to live indefinitely, into more specialized "progenitor" cells. In normal development, these progenitor cells give rise to very specific types of spinal neurons, but they do so for only short periods of time, because they lack the ability to continuously divide. With the newly added telomerase gene, the spinal progenitor cells were able to continuously divide while still producing only specific types of neurons. The outcome was a line of immortal progenitor cells, capable of churning out human spinal neurons indefinitely.
Tom Rickey | EurekAlert!
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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