There sits in most mammalian cells what amounts to a lock-box of DNA tucked away from the bulk of genetic material. While scientists routinely cut and paste snippets of lifes blueprint to learn more about life and to treat disease, crucial DNA within cellular structures known as mitochondria has remained off-limits.
Thats beginning to change, though, thanks in part to work described in the Feb. 10 issue of the Proceedings of the National Academy of Sciences by a team from the University of Rochester Medical Center and the University of Melbourne in Australia. Scientists created a new kind of mouse by replacing the genetic material in the mitochondria of one species with that from another in a gene-swapping exercise necessary if doctors are to understand several currently untreatable human diseases.
"What we call mitochondrial medicine – how specific mitochondrial mutations and deficiencies lead to disease – didnt even exist 15 years ago. Now the field is in its infancy. The ultimate goal is improved treatment for people with disorders that currently cant be treated," says Carl A. Pinkert, Ph.D., of the Center for Aging and Developmental Biology at Rochester, who led the Rochester team.
Tom Rickey | EurekAlert!
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In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
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A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
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