Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Making new muscle: Researchers in Rome produce a mouse that can regenerate its tissues

04.02.2004


Researchers at the European Molecular Biology Laboratory (EMBL) and the University of Rome "La Sapienza" have found a way to restore some of the "regenerative" ability of tissues, which happens naturally in animals at the embryonic stage of development, but is lost shortly after birth. The scientists’ work, published this week in PNAS, gives new insight into how stem cells can be mobilized across the body, and how they take on specialized functions in tissue.



"Many labs have reported the integration of stem cells into various types of tissues, but on a small scale," says Prof. Nadia Rosenthal, Coordinator of EMBL’s Mouse Programme in Monterotondo, Italy. "This is the first study to show that stem cells can be mobilized to achieve a major regeneration of damaged tissue."

In a collaboration with the group of Antonio Musarò at the University of Rome, the scientists investigated muscle tissue in mice, discovering that stem cells can travel large distances to reach an injury. They also found a special form of a protein called mIGF-1 induces the muscle to send the distress signal that summons them.


"This form of IGF-1 is produced in the cells of embryos, but that production shuts down quickly after birth," says Rosenthal. "It is also produced in quick bursts when muscles are injured. This made us think it might play a role in regenerating damaged tissues."

Trista Dawson | EMBL
Further information:
http://www.embl-heidelberg.de/ExternalInfo/oipa/pr2004/pr040204.pdf
http://www.embl.de

More articles from Life Sciences:

nachricht Building a brain, cell by cell: Researchers make a mini neuron network (of two)
23.05.2018 | Institute of Industrial Science, The University of Tokyo

nachricht Research reveals how order first appears in liquid crystals
23.05.2018 | Brown University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Molecular switch will facilitate the development of pioneering electro-optical devices

24.05.2018 | Power and Electrical Engineering

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>