Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Using fMRI technology to understand hyperlexia

08.01.2004


Georgetown University Medical Center researchers today published the first ever fMRI study of hyperlexia, a rare condition in which children with some degree of autism display extremely precocious reading skills. Appearing in Neuron, the case study uncovers the neural mechanisms that underlie hyperlexia, and suggest that hyperlexia is the true opposite of the reading disability dyslexia.

Hyperlexia is found in very rare cases in children who are on the "autism spectrum," meaning they display some characteristics of autism. Like autistic children, children with hyperlexia have extreme difficulty with oral communication, social interaction and expression, and yet can read surprisingly well at a very young age. By some accounts, hyperlexic children can read at 18 months, sometimes two years before they have ever uttered a single word. They are drawn to print, sometimes reading all the signs and license plates they might encounter during a brief walk through the parking lot.

The child in this case study, Ethan , reads six to eight years in advance of his age. He read dictionaries in his twos, but spoke his first word at age three and a half.



"This advanced reading ability, which would likely surprise any parent, is even more extraordinary given that many of these children begin reading before mastering spoken language, and sometimes before speaking at all," said senior author Guinevere Eden, DPhil, associate professor of pediatrics and director of Georgetown’s Center for the Study of Learning. "Current theories of reading development posit that decoding skills are based on linguistic abilities, but our finding suggests that children like Ethan are able to map sound onto print without a solid language basis."

Eden and her colleagues use fMRI technology to study how brains develop and function as children learn to read. Most children acquire reading skills through explicit instruction received over several years of schooling. In this study, the research team wanted to illucidate the neural signature for precocious reading, which arose in the absence of any teaching. Deviations from the normal pattern would suggest that other regions of the brain might have the potential to become involved in the reading process and would shed light onto possible compensatory strategies of the abnormally reading brain.

The hyperlexic boy, Ethan performed several reading tests while lying down in the fMRI. The researchers then compared hot spots of brain activity in Ethan as he performed these tasks against brain scans of typically developing readers, who were matched to Ethan on either chronological or reading age. Compared to these groups, Ethan demonstrated greater activity in an area on the left side of the brain that is associated with understanding the sounds of speech as well as a region on the right side of the brain that is part of the visual system.

Co-author Peter Turkeltaub, a PhD student, draws an analogy of to the volume control on a radio. "A region of the brain implicated in reading skills, the left superior temporal cortex, is like a dial. When the dial is turned up, you find accelerated readers, or hyperlexics. When the dial is turned down, as has been shown for dyslexic children, you find inefficient readers. The more neurological research we do, the better we may understand how the dial works and what educational interventions may turn the dial toward its optimum point."

Ethan’s parents knew something was peculiar with their son at a young age. He did not speak, make eye contact, or respond to typical verbal or non-verbal communications cues. However, he could sit silently in a corner and read books for hours.

Now at age eleven, Ethan attends a public school with an aide, and was recently voted class president. He has an insatiable curiosity for books, magazines, and television, but still has difficulty in social situations. According to his mom Ilene, "the other kids think he is very smart but very unusual. There are times when he says things that make the other kids realize he is not quite the same."

Ilene said, "If I could tell people one thing about hyperlexia, I would remind them that these children have a tremendous gift and that reading is the way to unlock their minds and hearts. Don’t try to take their books away to force them to interact with people. Encourage their reading ability, because they have so much to offer the world, just in a more unconventional way."

"Neuroscience is allowing us to better characterize people who were before all bundled under the general autism umbrella," said Eden. "Just as it is extremely helpful to distinguish a child with Asperberger’s, identification of hyperlexia can be equally as important for early intervention and appropriately tailored education."


This study was funded by the National Institutes of Health’s National Institute of Child Health and Human Development (NICHD) and National Association for Autism Research (NAAR).

Georgetown University Medical Center is an internationally recognized academic medical center with a three-part mission of research, teaching and patient care (through our partnership with MedStar Health). Our mission is carried out with a strong emphasis on public service and a dedication to the Catholic, Jesuit principle of cura personalis--or "care of the whole person." The Medical Center includes the School of Medicine and the School of Nursing and Health Studies, both nationally ranked, and the world renowned Lombardi Cancer Center.

The Georgetown Center for the Study of Learning, which is funded by the National Institutes of Health, seeks to better understand the neural mechanisms that enable the acquisition of reading skills, and to identify new approaches to assess and treat reading disabilities.

Lindsey Spindle | EurekAlert!
Further information:
http://www.georgetown.edu/gumc

More articles from Life Sciences:

nachricht A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>