Scientists at UCSFs Ernest Gallo Clinic and Research Center have identified a single brain protein that can account for most of the intoxicating effects of alcohol. The finding pinpoints perhaps the best target yet for a drug to block alcohols effect and potentially treat alcoholism, the scientists say.
The mechanisms by which alcohol acts on the brain are thought to be similar throughout the animal kingdom, since species from worms and fruit flies to mice and humans all become intoxicated at similar alcohol concentrations. But although studies have identified a number of genes that can partially influence how alcohol affects behavior, this is the first finding that a single gene and the brain protein it codes for - known as an ion channel - are responsible for the intoxicating effects of alcohol in a living organism, according to the researchers.
The discovery was made in a six-year research effort focusing on Caenorhabditis elegans, the roundworm widely studied because about half of its approximately 20,000 genes have counterparts in the human genome.
Wallace Ravven | EurekAlert!
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MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
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Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
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