A team of researchers at the Institute of Agricultural Biotechnology & Natural Resources, together with the Japanese pharmaceutical company, JCR Pharmaceuticals, have discovered an enzyme which could be fundamental in the metabolism of glycogen in mammals. This find may be the first step in the finding a cure for illnesses associated with metabolic disorders such as certain kinds of diabetes and cancer. The characterisation and identification of the gene that its codes has been recently published in an article in Biochemical Journal.
The research at the Institute of Agricultural Biotechnology & Natural Resources into the metabolism of starch in plants has inspired, amongst others, a series of studies aimed at a better understanding of the equivalent substance in bacteria and animals, i.e. glycogen.
Previously, the team led by Javier Pozueta Romero had managed to identify an enzyme which impedes the production of starch in plants and which was given the name ADP-glucose pyrophosphatase. This time the research team has identified this enzyme which specifically recognises UDP glucose, a molecule essential for life, given that it is necessary for the synthesis of glycogen, glycoproteins and glycolipids. According to the researchers, ADP-glucose pyrophosphatase would be the enzyme responsible for regulating levels of the UDP glucose needed for the formation of glycogen in animals.
Toward a 'smart' patch that automatically delivers insulin when needed
18.01.2017 | American Chemical Society
127 at one blow...
18.01.2017 | Stiftung Zoologisches Forschungsmuseum Alexander Koenig, Leibniz-Institut für Biodiversität der Tiere
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
18.01.2017 | Power and Electrical Engineering
18.01.2017 | Materials Sciences
18.01.2017 | Life Sciences