A team of researchers at the Institute of Agricultural Biotechnology & Natural Resources, together with the Japanese pharmaceutical company, JCR Pharmaceuticals, have discovered an enzyme which could be fundamental in the metabolism of glycogen in mammals. This find may be the first step in the finding a cure for illnesses associated with metabolic disorders such as certain kinds of diabetes and cancer. The characterisation and identification of the gene that its codes has been recently published in an article in Biochemical Journal.
The research at the Institute of Agricultural Biotechnology & Natural Resources into the metabolism of starch in plants has inspired, amongst others, a series of studies aimed at a better understanding of the equivalent substance in bacteria and animals, i.e. glycogen.
Previously, the team led by Javier Pozueta Romero had managed to identify an enzyme which impedes the production of starch in plants and which was given the name ADP-glucose pyrophosphatase. This time the research team has identified this enzyme which specifically recognises UDP glucose, a molecule essential for life, given that it is necessary for the synthesis of glycogen, glycoproteins and glycolipids. According to the researchers, ADP-glucose pyrophosphatase would be the enzyme responsible for regulating levels of the UDP glucose needed for the formation of glycogen in animals.
Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard
New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
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