Identification of Jelly Belly gene may lead to new drugs to combat heart disease, cancer and neurological disorders
Researchers at Oregon Health & Science University (OHSU) have identified a secreted signaling protein that regulates smooth muscle development in fruit flies. In the absence of a protein called "Jelly Belly (Jeb)," primitive smooth muscle cells fail to migrate or differentiate, according to study results published in the October 2 issue of Nature.
"Our research shows that Jelly Belly is required for the normal development of the smooth muscle that surrounds the gut in flies and we are investigating it in the arteries of mammals. It is also related to the development of heart muscle," said Joseph B. Weiss M.D., Ph.D., principal investigator and assistant professor (molecular medicine and cardiology), and Heart Research Center scientist in the OHSU School of Medicine.
Smooth muscles are involved in involuntary but essential functions, such as digestion and control of blood flow. Unlocking the genetic mechanisms controlling their embryonic development may allow scientists to understand better what triggers their abnormal growth. Human disorders that are linked to abnormal smooth muscle growth or function include high blood pressure, arteriosclerosis and congenital heart defects.
Christine Pashley | EurekAlert!
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Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
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