In 1984, HARBOR BRANCH scientists exploring deep waters off the Bahamas in one of the institutions Johnson-Sea-Link submersibles discovered a small piece of sponge that harbored a chemical with a remarkable ability to kill cancer cells in laboratory tests. Despite almost two decades of searching, though, the group was never able to find enough of the sponge to fully explore its potential. But now that process can finally begin because, thanks to some creative detective work, the team has found the animals secret hiding place and collected enough of it to support years of intense research.
The Johnson-Sea-Link I submersible, used to collect the promising sponge
Credit: HARBOR BRANCH
Amy Wright,director of Harbor Branch Biomedical Marine Research (right) and Shirley Pomponi, Harbor Branch vice-president and director of research, aboard the R/V Seward Johnson II sorting samples after a drug discovery submersible dive.
Credit: HARBOR BRANCH
"Its just amazing," says Amy Wright, director of HARBOR BRANCH Biomedical Marine Research, of the sponge she has been on a career-long quest to find. "This is our next cure, I know its our next cure."
A chemical produced within the sponge, which has not yet been given an official name, has proven in one test of cancer-fighting potential to be about 400 times more potent than Taxol®, a widely used treatment for breast and other forms of cancer. As important, preliminary experiments have also shown the compound to be fairly non-toxic to normal cells.
Mark Schrope | EurekAlert!
Researchers uncover protein-based “cancer signature”
05.12.2016 | Universität Basel
The Nagoya Protocol Creates Disadvantages for Many Countries when Applied to Microorganisms
05.12.2016 | Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
05.12.2016 | Earth Sciences
05.12.2016 | Physics and Astronomy
05.12.2016 | Life Sciences