Johns Hopkins researchers have uncovered a key step in the bodys regulation of melatonin, a major sleep-related chemical in the brain. In the advance online section of Nature Structural Biology, the research team reports finding the switch that causes destruction of the enzyme that makes melatonin -- no enzyme, no melatonin.
Melatonin levels are high at night and low during the day. Even at night, melatonin disappears after exposure to bright light, a response that likely contributes to its normal daily cycle, but plagues shift workers and jet setters by leading to sleeplessness. To help understand melatonins light-induced disappearance, the Hopkins researchers turned to the enzyme that makes it, a protein called AANAT.
One way cells turn proteins like AANAT on and off is by modifying them, attaching or removing small bits, such as phosphate groups, to particular spots along the proteins backbone. For AANAT, the key spot turns out to be building block number 31, the researchers have found.
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Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
On 15 March, the AWI research aeroplane Polar 5 will depart for Greenland. Concentrating on the furthest northeast region of the island, an international team...
The world’s second-largest ice shelf was the destination for a Polarstern expedition that ended in Punta Arenas, Chile on 14th March 2018. Oceanographers from...
At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.
When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...
At the ILA Berlin, hall 4, booth 202, Fraunhofer FHR will present two radar sensors for navigation support of drones. The sensors are valuable components in the implementation of autonomous flying drones: they function as obstacle detectors to prevent collisions. Radar sensors also operate reliably in restricted visibility, e.g. in foggy or dusty conditions. Due to their ability to measure distances with high precision, the radar sensors can also be used as altimeters when other sources of information such as barometers or GPS are not available or cannot operate optimally.
Drones play an increasingly important role in the area of logistics and services. Well-known logistic companies place great hope in these compact, aerial...
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