A study conducted by University of Utah genetics researchers shows that the steroid hormone ecdysone controls an important phase in the embryonic development of insects, providing an unexpected parallel with the role of the hormone in controlling metamorphosis. The studys findings also give scientists new insights into how steroids control maturation in higher organisms.
Carl S. Thummel, Ph.D., a Howard Hughes Medical Institute investigator and professor of human genetics at the University of Utah School of Medicine, said that although other studies have established a critical role for ecdysone in controlling insect metamorphosis, very little was known about roles for the hormone during embryonic development.
To find the answer, Thummel and Tatiana Kozlova, a Howard Hughes Medical Institute research associate, looked at the activation pattern of the receptor for ecdysone. They found that this receptor is highly activated in an extraembryonic tissue called amnioserosa, a tissue that does not itself form part of the embryo, but is nonetheless required for embryonic development. Thummel said the source of ecdysone in the early embryo, prior to the development of the insect endocrine organ, has always baffled scientists. "Our findings suggest that the earliest source of hormone is the amnioserosa," he said, "although other sources are likely to contribute at later times."
Cindy Fazzi | EurekAlert!
Cryo-electron microscopy achieves unprecedented resolution using new computational methods
24.03.2017 | DOE/Lawrence Berkeley National Laboratory
How cheetahs stay fit and healthy
24.03.2017 | Forschungsverbund Berlin e.V.
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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