Probably, animals and human beings possess a biochemical vehicle for measuring life span. The key role in this vehicle is played by a short DNA - chronomere. The chronomeric ageing theory, based on tremendous experimental material, has been developed with support of the Russian Foundation for Basic Research.
Early in the 70s of the 20th century, Russian researcher Alexy Olovnikov forecast existence of the chromosomes end sequences - telomer, which shorten after each cell division. Aa lot of scientists believe now that telomer shortening leads to cell ageing. However, A.M. Olovnikov is convinced that telomer shortening is only the witness of ageing, and special DNA molecules – chronomeres - are responsible for ageing processes. Chronomeres are located in non-dividing cells of the cerebrum. So far, this is only a hypothesis based on the tremendous experimental material collected by Russian and foreign researches within the recent years.
The chronomere – is a copy of a tiny sector of a chromosome’s DNA. Its length makes, apparently, 10 to15 thousand pairs of nucleotides. The chronomere is covered by proteins and lies in a special cavity, like in a nest, between coils of the chromosome which gave birth to it, the chronomere being tied up with the chromosome by chemical bonds. The chronomere contains several genes, from which a special enzyme (RNA-polymerase) prints short RNA molecules. These RNAs interact with certain chromosome’s genes, influence their activity, and, consequently, affect the entire cell’s activity.
Sergey Komarov | Informnauka
Researchers invent tiny, light-powered wires to modulate brain's electrical signals
21.02.2018 | University of Chicago
The “Holy Grail” of peptide chemistry: Making peptide active agents available orally
21.02.2018 | Technische Universität München
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
21.02.2018 | Life Sciences
21.02.2018 | Life Sciences
21.02.2018 | Materials Sciences