Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Body Scanners for Lab Animals

29.08.2003


A PET (positron emission tomography) scanner sensitive enough to use on laboratory mice has been developed by biomedical engineers at UC Davis. The device is already being used for studies on prostate cancer.


This MicroPET scan of a live rat shows the skeleton.



"We think it’s the highest resolution scanner in existence. We can see things we couldn’t see before," said Simon Cherry, professor of biomedical engineering at UC Davis, who leads the research group.

PET scanners have become widely used in medical imaging, alongside X-rays, CAT scans and magnetic resonance imaging, because they can give information about metabolic activity in body tissues. The machines used for scanning people cannot see sufficiently fine detail for use on small animals such as mice and rats.


The current machine, called MicroPET II, can resolve a volume of about one cubic millimeter, or one microliter, Cherry said. That represents an approximately eight-fold improvement over an earlier device built by Cherry’s laboratory at UCLA, before moving to UC Davis in 2001.

PET works by detecting short-lived radioactive tracers that emit positrons, or anti-electrons. Those tracers can be attached to other molecules that are targeted to particular cells. For example, highly active cells, such as cancer cells, can be tagged with radioactive glucose.

Non-invasive imaging technology such as PET allows researchers to gain more information and to use fewer animals in experimental studies. For example, researchers could use an experimental drug to treat cancer in mice and see if the tumors were shrinking. Without methods such as PET, small deposits of cancer cells are hard to detect in experimental animals.

Cherry presented the work at the annual meeting of the Society for Molecular Imaging in San Francisco, Aug. 15-18. The work has also been published in the journal Physics in Medicine and Biology.


Media contact(s):
Andy Fell, UC Davis News Service, (530) 752-4533, ahfell@ucdavis.edu


Andy Fell | UC DAvis
Further information:
http://www.news.ucdavis.edu/search/news_detail.lasso?id=6630

More articles from Life Sciences:

nachricht eTRANSAFE – collaborative research project aimed at improving safety in drug development process
26.09.2017 | Fraunhofer-Gesellschaft

nachricht Beer can lift your spirits
26.09.2017 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The fastest light-driven current source

Controlling electronic current is essential to modern electronics, as data and signals are transferred by streams of electrons which are controlled at high speed. Demands on transmission speeds are also increasing as technology develops. Scientists from the Chair of Laser Physics and the Chair of Applied Physics at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have succeeded in switching on a current with a desired direction in graphene using a single laser pulse within a femtosecond ¬¬ – a femtosecond corresponds to the millionth part of a billionth of a second. This is more than a thousand times faster compared to the most efficient transistors today.

Graphene is up to the job

Im Focus: LaserTAB: More efficient and precise contacts thanks to human-robot collaboration

At the productronica trade fair in Munich this November, the Fraunhofer Institute for Laser Technology ILT will be presenting Laser-Based Tape-Automated Bonding, LaserTAB for short. The experts from Aachen will be demonstrating how new battery cells and power electronics can be micro-welded more efficiently and precisely than ever before thanks to new optics and robot support.

Fraunhofer ILT from Aachen relies on a clever combination of robotics and a laser scanner with new optics as well as process monitoring, which it has developed...

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Bacterial Nanosized Speargun Works Like a Power Drill

26.09.2017 | Life Sciences

The fastest light-driven current source

26.09.2017 | Physics and Astronomy

Beer can lift your spirits

26.09.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>