Anyone who made it to high school biology has learned about mitosis, or cell division. One cell divides into two, two into four and so forth in a process designed to pass on exact copies of the DNA in chromosomes to daughter cells. New research, by a University of Georgia team, shows how the genes that control this process are regulated.
The study is important for cancer research because the regulation of cell division goes awry in tumors and normal cell growth and behavior are lost. Understanding how normal cell division is regulated will allow scientists to identify potential targets for cancer therapeutics, said Stephen Dalton, the molecular geneticist who led the UGA team.
"This is fundamental molecular cancer research," Dalton said. "One major problem in cancer is mis-segregation, [when the cells] ability to equally divide chromosomes is lost. One [daughter] cell might get too much genetic information and the other too little.
Kim Carlyle | EurekAlert!
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The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
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