After immunofluorescent staining with two antibodies, the protein XCAP-D2 is evident in red on the lampbrush chromosomes (green) in the nucleus of a frog oocyte. The red signal is associated with highly condensed but transcriptionally inactive regions, while the green indicates long loops of intense transcription.
Photo courtesy of Michel Bellini
Researchers studying the nuclei of frog oocytes in early stages of meiosis -- the cell division that gives rise to germ cells -- have found that two key proteins remain apart at a crucial time before condensation occurs. One of the proteins, they say, may be important in the early organization of chromosomes and later may recruit the other.
In the August issue of the journal Chromosome Research, scientists at the University of Illinois at Urbana-Champaign detail how they used antibodies to the proteins, XCAP-E and XCAP-D2, and confocal laser scanning microscopy to zero in on the proteins’ precise locations inside the nuclei of gametes of the African frog Xenopus laevis.
(The research will be on display as a poster presentation Aug. 17-22 during the Gorden Research Conference on Plasmid & Chromosome Dynamics in Tilton, N.J.)
Jim Barlow | UIUC
One step closer to reality
20.04.2018 | Max-Planck-Institut für Entwicklungsbiologie
The dark side of cichlid fish: from cannibal to caregiver
20.04.2018 | Veterinärmedizinische Universität Wien
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
20.04.2018 | Physics and Astronomy
20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy