Led by UCLA physiologist H. Ronald Kaback (Sherman Oaks), an international research teams 12-year mission to solve the structure of an important protein has paid off. Kaback and his colleagues recently captured the three-dimensional structure of lactose permease (LacY), which moves lactose across the cell membrane of E. coli, a common bacterium.
According to Kaback, LacY is a model for a large family of related transport proteins, many of which are associated with human disease.
"We hope that the structure of LacY will offer a useful tool by enabling scientists to understand how other membrane transport proteins work," said Kaback, a professor of physiology and microbiology, immunology and molecular genetics at the David Geffen School of Medicine at UCLA and a Howard Hughes Medical Institute investigator.
Elaine Schmidt | EurekAlert!
A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau
On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
18.08.2017 | Life Sciences
18.08.2017 | Physics and Astronomy
18.08.2017 | Materials Sciences