The image displays a single Arabidopsis mutant line from the Salk Institute insertion mutant collection/database. The location of the Agrobactrium T-DNA insertion is known from sequencing of The image displays a single Arabidopsis mutant line from the Salk Institute insertion mutant collection/database. The location of the Agrobactrium T-DNA insertion is known from sequencing of the genome.
Credit: Kent Schnoeker, The Salk Institute
The image depicts the locations of Agrobacterium T-DNA insertions (triangles) in a small segment of one Arabidopsis chromosome. The locations of individual predicted genes (top line) and the transcription units (bottom line) are indicated by the multi-colored boxes.
Credit: Huaming Chen/Joseph Ecker
Scientists have inactivated almost three-quarters of all genes in the genome of Arabidopsis thaliana, a species widely used in plant research. The feat, which results in the largest so-called "knockout" gene collection of a complex multi-cellular organism, now allows researchers to study the function of each of those genes individually or together.
The findings, published in the August 1 issue of the journal Science, mark an important milestone in the field of plant genomics. Following the release of the Arabidopsis genome sequence in 2000, the National Science Foundation (NSF) jump started the next phase of plant genome research, instituting the Arabidopsis 2010 Project to determine the location and function of each and every Arabidopsis gene by the year 2010. Knowing the function of all the genes in this model plant will aide scientists immensely in their work to improve disease resistance, control how quickly or slowly fruit will ripen, and create healthier and improved crops.
Joe Ecker at the Salk Institute for Biological Studies and his research team created knockouts, or inactivating mutations, in 21,700 of the estimated 29,454 Arabidopsis genes. Knocking out a gene or group of genes allows scientists to observe what goes wrong in the mutant plant and determine what function the inactivated gene(s) had in the plant system.
Andrea Spiker | National Science Foundation
BigH1 -- The key histone for male fertility
14.12.2017 | Institute for Research in Biomedicine (IRB Barcelona)
Guardians of the Gate
14.12.2017 | Max-Planck-Institut für Biochemie
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
14.12.2017 | Health and Medicine
14.12.2017 | Physics and Astronomy
14.12.2017 | Life Sciences