Researchers looking inside a pathogenic soil bacterium have found an organelle, a subcellular pouch, existing independently from the plasma membrane. The discovery within a prokaryotic organism challenges the theory on the origin of eukaryotic organelles and suggests a targeted approach to killing many disease-causing organisms.
Acidocalcisomes (the black spheres) as viewed in a trypanosome, a family of parasites that cause African sleeping sickness, Chagas disease and leishmaniasis and the first organisms where Docampo found this organelle. The cell is approximately 10 microns long and 4 microns wide. Courtesy of Kildare Miranda
"The organelle we found in the bacterium Agrobacterium tumefaciens is practically identical to the organelle called acidocalcisome in unicellular eukaryotes," said Roberto Docampo, a professor of veterinary pathobiology in the College of Veterinary Medicine at the University of Illinois at Urbana-Champaign.
Docampo began researching these organelles in 1994. He soon determined that a tiny granule in yeast, fungi and bacteria, thought to be for storage, was a fully operational organelle containing pyrophosphatase, a pump-like enzyme that allows proton transport. He named it an acidocalcisome for its acidic and calcium components. In 2000, he reported its existence in Plasmodium berghei, a malaria-causing eukaryotic parasite.
Jim Barlow | UIUC
Biologists unravel another mystery of what makes DNA go 'loopy'
16.03.2018 | Emory Health Sciences
Scientists map the portal to the cell's nucleus
16.03.2018 | Rockefeller University
Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
On 15 March, the AWI research aeroplane Polar 5 will depart for Greenland. Concentrating on the furthest northeast region of the island, an international team...
The world’s second-largest ice shelf was the destination for a Polarstern expedition that ended in Punta Arenas, Chile on 14th March 2018. Oceanographers from...
At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.
When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...
At the ILA Berlin, hall 4, booth 202, Fraunhofer FHR will present two radar sensors for navigation support of drones. The sensors are valuable components in the implementation of autonomous flying drones: they function as obstacle detectors to prevent collisions. Radar sensors also operate reliably in restricted visibility, e.g. in foggy or dusty conditions. Due to their ability to measure distances with high precision, the radar sensors can also be used as altimeters when other sources of information such as barometers or GPS are not available or cannot operate optimally.
Drones play an increasingly important role in the area of logistics and services. Well-known logistic companies place great hope in these compact, aerial...
16.03.2018 | Event News
13.03.2018 | Event News
08.03.2018 | Event News
16.03.2018 | Earth Sciences
16.03.2018 | Physics and Astronomy
16.03.2018 | Life Sciences