Dr. Wesley Sundquist, professor of biochemistry at the University of Utah, will present at the Experimental Biology 2003 meeting in San Diego on his work in elucidating how HIV is manufactured and assembled in the cell.
The raison dêtre of a virus such as HIV, if a non-living thing can be said to have one, is to turn a host cell into a factory that churns out virus copies and releases them to infect other cells. Dr. Sundquists research has focused on discovering the mechanisms underlying this manufacturing process.
By identifying and characterizing the structures of specific cellular proteins that are crucial to assembling HIV, Dr. Sundquist is providing potential new targets for future anti-HIV drugs. For example, he and his colleagues were the first to show that a protein called TSG101 is required for HIV release. HIV needs TSG101 in order to escape from its host cell in a process termed budding. Dr. Sundquists team has also determined the structure of the part of TSG101 to which HIV binds. Finding ways to alter this structure or otherwise block its binding to HIV theoretically would prevent budding and slow or halt the infection.
Sarah Goodwin | EurekAlert!
Cancer diagnosis: no more needles?
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25.05.2018 | Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)
The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.
Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
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