Researchers in Oxford University’s Department of Human Anatomy have identified a factor involved in the regeneration of neurons in the central nervous system. The discovery and use of this factor could provide the basis for a reparative treatment for both brain and spinal cord injuries.
Unlike lower vertebrates, mammals have lost the ability to repair damage to the brain and spinal cord. Since peripheral nerves are capable of repair, this is thought to be not so much an intrinsic inability of central nervous system (CNS) tissue to repair itself, but rather an environment in the CNS that is hostile to regeneration. This inhibition of neuronal regeneration is a result of a number of factors including axotomy-induced cell death, a gliotic scar that provides a physical barrier to regeneration as well as an environment that is inhibitory to growth. A number of strategies have been employed in the past to overcome this inhibition, including: blocking apoptosis, stem cell therapy, grafting of peripheral nervous system (PNS) cells and delivery of neurotrophic factors. However, the results of these animal studies have been controversial with regard to their claims of significant functional recovery.
Following a great deal of work on the action of Schwann cell conditioned medium (SCCM), which previous research has shown to support the re-growth of neuronal cells, the Oxford inventors have now identified a factor that is responsible for stimulation of neuronal re-growth and have demonstrated its effectiveness for both peripheral and central nervous system neurons. Use of this factor or its analogues may provide the basis for a reparative treatment for brain and spinal cord injury.
Jennifer Johnson | alfa
Cells migrate collectively by intermittent bursts of activity
30.09.2016 | Aalto University
The structure of the BinAB toxin revealed: one small step for Man, a major problem for mosquitoes!
30.09.2016 | CNRS (Délégation Paris Michel-Ange)
Friction stir welding is a still-young and thus often unfamiliar pressure welding process for joining flat components and semi-finished components made of light metals.
Scientists at the University of Stuttgart have now developed two new process variants that will considerably expand the areas of application for friction stir welding.
Technologie-Lizenz-Büro (TLB) GmbH supports the University of Stuttgart in patenting and marketing its innovations.
Friction stir welding is a still-young and thus often unfamiliar pressure welding process for joining flat components and semi-finished components made of...
Optical quantum computers can revolutionize computer technology. A team of researchers led by scientists from Münster University and KIT now succeeded in putting a quantum optical experimental set-up onto a chip. In doing so, they have met one of the requirements for making it possible to use photonic circuits for optical quantum computers.
Optical quantum computers are what people are pinning their hopes on for tomorrow’s computer technology – whether for tap-proof data encryption, ultrafast...
The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.
“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...
With the help of artificial intelligence, chemists from the University of Basel in Switzerland have computed the characteristics of about two million crystals made up of four chemical elements. The researchers were able to identify 90 previously unknown thermodynamically stable crystals that can be regarded as new materials. They report on their findings in the scientific journal Physical Review Letters.
Elpasolite is a glassy, transparent, shiny and soft mineral with a cubic crystal structure. First discovered in El Paso County (Colorado, USA), it can also be...
For the first time, Fraunhofer IKTS shows additively manufactured hardmetal tools at WorldPM 2016 in Hamburg. Mechanical, chemical as well as a high heat resistance and extreme hardness are required from tools that are used in mechanical and automotive engineering or in plastics and building materials industry. Researchers at the Fraunhofer Institute for Ceramic Technologies and Systems IKTS in Dresden managed the production of complex hardmetal tools via 3D printing in a quality that are in no way inferior to conventionally produced high-performance tools.
Fraunhofer IKTS counts decades of proven expertise in the development of hardmetals. To date, reliable cutting, drilling, pressing and stamping tools made of...
30.09.2016 | Event News
29.09.2016 | Event News
28.09.2016 | Event News
30.09.2016 | Life Sciences
30.09.2016 | Life Sciences
30.09.2016 | Earth Sciences