Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sometimes no result is good result for science

28.03.2003


Sometimes finding out what doesn’t matter in science is just as important as finding what does.

That’s the case for a study that looked at the function of the viral protein, MTase1. Researchers found that the rate of virus replication in tissue culture was not affected when MTase1 was removed.

The finding is important as researchers look for what proteins are essential and how they function in cells, potentially providing answers to everything from insect control to the control of human diseases such as smallpox.



"How do viruses replicate? When there is an infection, one virus gets into one cell, and makes the cell synthesize viral proteins and viral DNA instead of what the cell needs to survive," said Dr. Linda Guarino, a Texas Agricultural Experiment Station biochemist and entomologist whose research with graduate student Xiaofeng Wu appears in this month’s Journal of Virology. "So, we want to understand how the virus manages to take over cells and force them to make more virus.

"We have to characterize the functions of individual viral proteins and how they interact with cellular proteins to understand this process," she noted.

Guarino and Wu studied MTase1 (methyltransferase) in the polyhedrosis virus of Autographa californica, a common moth species whose caterpillar feeds on alfalfa, sugar beets, tobacco and tomato crops. The insect has played an important role in research on viruses and their use as an environmentally friendly means of pest control, since the polyhedrosis virus was originally isolated from its larvae more than 30 years ago.

"MTase1 is structurally similar to a protein that poxvirus makes, and also in the poxvirus, it is non essential," Guarino said. "So, we know the virus makes proteins that are not essential when tested in a lab. However, we only studied replication in tissue culture, which is not the natural setting for replication. It might be essential in animals, so that will need to be researched as well."

She said the goal is to find out what proteins are essential, what they need to make RNA, and what their functions are.

Kathleen Phillips | Texas A&M University
Further information:
http://agnews.tamu.edu/dailynews/stories/BIOT/Mar2703a.htm

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>