Researchers hope to someday develop an enzyme to repair UV-damaged DNA in humans
Plants, pond scum, and even organisms that live where the sun doesnt shine have something that humans do not -- an enzyme that repairs DNA damaged by ultraviolet (UV) light.
Cabell Jonas of Richmond, Va., an undergraduate honors student in biology at Virginia Tech, will report on the molecular details of the DNA-repair enzyme at the 225th national meeting of the American Chemical Society March 23-27 in New Orleans. Her poster includes the novel discovery that the enzyme does not operate the same way in different organisms.
UV light is one of the most prevalent causes of DNA damage. In humans, incidents of resulting disease -- in particular, skin cancer, are increasing as exposure to UV increases, says Sunyoung Kim, assistant professor of biochemistry at Virginia Tech. Since the human body does not have DNA photolyase, Kim and her students are studying the DNA-repair enzyme in other systems. "Our aim is to map the molecular interactions and understand the structural changes, with the eventual goal of being able to create or adapt this flavoenzyme from another organism for treatment of skin cancer in humans," says Kim.
Sunyoung Kim | EurekAlert!
At last, butterflies get a bigger, better evolutionary tree
16.02.2018 | Florida Museum of Natural History
New treatment strategies for chronic kidney disease from the animal kingdom
16.02.2018 | Veterinärmedizinische Universität Wien
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...
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