Atomic model of a glucose oxidase enzyme molecule. This enzyme oxidizes glucose and produces electrons that can be channeled into an electrode through a gold nanoparticle connection. This system can be used to better detect glucose for diabetic patients. The technique might also be applied in the rapid and inexpensive detection of pollutants, infections, disease markers, or agents of bioterrorism
Three molecules of glucose oxidase, two wired with gold nanoparticles (yellow, indicated by arrows), visualized with the scanning transmission electron microscope (STEM) in Brookhaven Labs biology department
Could yield biosensors with greater sensitivity, specificity
Scientists at Hebrew University, Israel, in collaboration with researchers at the U.S. Department of Energy’s Brookhaven National Laboratory, have devised a way to use gold nanoparticles as tiny electrical wires to plug enzymes into electrodes. The gold “nanoplugs” help align the molecules for optimal binding and provide a conductive pathway for the flow of electrons. The research, described in the March 21, 2003, issue of Science, may yield more sensitive, inexpensive, noninvasive detectors for measuring biological molecules, including, potentially, agents of bioterrorism.
The idea behind the technology, says Brookhaven biologist Jim Hainfeld, who developed the gold nanoparticles and the means of attaching them to other molecules, is to measure the current as an indicator of the number of biological molecules involved in the reaction.
Karen McNulty Walsh | DOE/BNL
Cells communicate in a dynamic code
19.02.2018 | California Institute of Technology
Studying mitosis' structure to understand the inside of cancer cells
19.02.2018 | Biophysical Society
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
19.02.2018 | Materials Sciences
19.02.2018 | Materials Sciences
19.02.2018 | Life Sciences