Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Improved Method for Separation of Organic Isomers

11.02.2003


Researchers in Oxford University’s Department of Inorganic Chemistry have devised a novel method for separating polar organic compounds, providing a useful alternative to the usual methods of chromatography or crystallisation.



The separation of mixtures of organic and inorganic compounds is of considerable importance in most areas of industrial and academic chemistry. In particular, isomeric mixtures are often difficult to separate and can require highly specialised techniques.

Conventional separation techniques involving chromatography or absorption are capable of removing impurities from process streams. Isomeric mixtures can be separated by crystallisation and other methods, but this is usually difficult due to the similar physical properties of the isomers. Any improvement in the efficiency or selectivity of a separation process can lead to increased product purity and significant cost savings.


The new Oxford technique provides a straightforward and novel method for separating polar organic compounds, and is a useful alternative to the usual methods of chromatography or crystallisation. Layered materials have been used for the intercalation of organic and inorganic species, principally with reference to specific clays. Specifically, layered double hydroxides have been used for the separation of 1,2- and 1,3- and 1,4-benzenedicarboxylic acids in greater than 95% selectivity. Research has continued, and in excess of 99% separation of 1,5-naphthalene sulphonate over the 2,6- isomer has been observed. Similar separations have been achieved for benzenedisulphonate. Differences in the intercalation rates between the mono- and di- substituted isomers have enabled a selectivity series to be devised. Work is ongoing to further evaluate this useful technique for isomer separation.

Isis Innovation, Oxford University’s technology transfer company, has filed a patent application for this technology and welcomes contact from companies interested in commercial exploitation.

Jennifer Johnson | alfa
Further information:
http://www.isis-innovation.com/licensing/476.html

More articles from Life Sciences:

nachricht Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard

nachricht New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>