Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

’Sticky’ DNA crystals promise new way to process information

07.02.2003


Imagine information stored on something only a hundredth the size of the next generation computer chip--and made from nature’s own storage molecule, DNA. A team led by Richard Kiehl, a professor of electrical engineering at the University of Minnesota, has used the selective "stickiness" of DNA to construct a scaffolding for closely spaced nanoparticles that could exchange information on a scale of only 10 angstroms (an angstrom is one 10-billionth of a meter). The technique allows the assembly of components on a much smaller scale and with much greater precision than is possible with current manufacturing methods, Kiehl said. The work is published in a recent issue of the Journal of Nanoparticle Research.



"In a standard silicon-based chip, information processing is limited by the distance between units that store and share information," said Kiehl. "With these DNA crystals, we can lay out devices closely so that the interconnects are very short. If nanoparticles are spaced even 20 angstroms apart on such a DNA crystal scaffolding, a chip could hold 10 trillion bits per square centimeter--that’s 100 times as much information as in the 64 Gigabit D-RAM memory projected for 2010. By showing how to assemble nanoscale components in periodic arrangements, we’ve taken the first step toward this goal."

Eventually, a chip made from DNA crystals and nanoparticles could be valuable in such applications as real-time image processing, Kiehl said. Nanocomponents could be clustered in pixel-like "cells" that would process information internally and also by "talking" to other cells. The result could be improved noise filtering and detection of edges or motion. Someday, the technology may even help computers identify images with something approaching the speed of the human eye and brain, said Kiehl.


The team devised a DNA scaffolding for arrays of nanoparticles of gold, but the scaffolding could also hold arrays of carbon nanotubes or other molecules. Information could be stored as an electrical charge on certain nanoparticles; the presence or absence of charge would constitute one bit of information. Alternatively, nanoparticles could be magnetic, and the magnetic states would be read as information. Because DNA strands contain four chemical bases spaced every 3.4 angstroms, information might be stored on that small a scale, Kiehl said.

To manufacture the scaffolding, the researchers took advantage of the fact that each base spontaneously pairs up with, or "sticks to," one of the other bases to form the famous DNA double helix. The team synthesized four different two-dimensional "tiles" of DNA, each tile having an extension that sticks to the extension on another tile. Like self-assembling jigsaw pieces, the tiles joined themselves into a flat crystal with a repeating pattern. One tile had a stretch of DNA that extended above the plane of the tile; to this the researchers anchored a spherical, 55-atom nanoparticle of gold. Under an electron microscope, the gold nanoparticles appeared as regular lines of bright spots. A regular pattern of nanoparticles is important in arranging them to process or store information.

"Gold is a metal, and a matrix between metals and organic molecules like DNA is very hard to make," Kiehl said. "If we can make DNA scaffolding for gold, we think we can do it for carbon nanotubes and other organic molecules. The technique is well suited to laying out locally interconnected circuitry, which is of great interest for circumventing the interconnect bottleneck-- the well-known problem where wires, rather than devices (transistors), limit computing speed."

Other scientists have used DNA as nanoparticle "glue," but such arrangements are prone to structural flaws, which limits their usefulness, said Kiehl. In contrast, the virtually perfect arrangement of molecules within a DNA crystal allows precise control over the arrangement of the particles.

Among the next steps for the researchers is to demonstrate that nanoparticles bound to the DNA crystals can function electrically.

"We’re working on instrumentation to do electrical characterization of gold nanoparticles and other nanocomponents on DNA," said Kiehl. "We hope to show, for example, that DNA doesn’t interfere with the electrical functioning of the nanocomponents."

The work was supported by the National Science Foundation.

Deane Morrison | EurekAlert!
Further information:
http://www.umn.edu/

More articles from Life Sciences:

nachricht Water forms 'spine of hydration' around DNA, group finds
26.05.2017 | Cornell University

nachricht How herpesviruses win the footrace against the immune system
26.05.2017 | Helmholtz-Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>