Researchers at the University of California, San Diego (UCSD) School of Medicine have identified an over-active gene and the molecular events it triggers to cause acquired cases of pulmonary hypertension, a form of high blood pressure in the lungs that kills about one percent of the population each year.
The findings, published in the February 6, 2003 issue of the New England Journal of Medicine, offer the first specific molecular targets for development of new therapies.
"Although a small subset of patients benefit from surgery to remove blood clots from the lungs, currently the only treatment for most types of pulmonary hypertension is lung transplantation," said the studys senior author Patricia Thistlethwaite, M.D., Ph.D., an assistant professor in the UCSD Division of Cardiothoracic Surgery.
Sue Pondrom | EurekAlert!
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