The Purdue University research team that recently created a tiny motor out of synthetic biological molecules has found further evidence that RNA molecules can perform physical work, a discovery that could advance nanotechnology and possibly solve fundamental mysteries about life itself.
One promising application of RNA-ATP binding is this microscopic motor, assembled by Peixuan Guos team at Purdue University. The motor, only a few nanometers wide, is formed by six strands of RNA surrounding an "axle" made of DNA. When fed a supply of ATP as fuel, the RNA molecules kick against the DNA in succession, much like the pistons in a conventional motor. (Graphic/Guo Laboratory)
Purdues Peixuan Guo has discovered how viral RNA molecules bind an energy-bearing organic molecule known as ATP. While linking these two substances might seem to create no more than a longer string of letters, the upshot is that now one of lifes most mysterious and ancient storehouses of information can be moved by one of its most important fuels. The discovery could shed light on the fundamental role RNA plays in the creation of living things.
"RNA could be even more of a key player than we realize," said Guo, professor of veterinary pathobiology in Purdues School of Veterinary Medicine. "The fact that it can be made to bind ATP in the phi29 virus could imply that these two molecules were among the first to partner in Earths dance of life."
Chad Boutin | EurekAlert!
Glycosylation: Mapping Uncharted Territory
21.09.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH
Molecular Force Sensors
20.09.2017 | Max-Planck-Institut für Biochemie
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
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