University of Minnesota researchers, with collaborators at the U. S. Department of Agricultures National Animal Disease Center in Ames, Iowa, have completed sequencing the genome of the bacteria that causes Johnes disease, a major chronic wasting disease found in dairy cattle. The bacterium, Mycobacterium paratuberculosis, is considered one of the most important threats to the health of dairy cattle worldwide and may represent a potential risk to the safety of the milk supply. The gene sequencing will allow researchers to develop new ways of early diagnosis, prevention and treatment of a disease that costs the dairy industry more than $200 million a year. The results of the sequencing analysis are available online at www.pathogenoics.umn.edu, and more about Johnes disease can be found at www.johnes.org.
"This is a horrible, hard to diagnose disease, largely because we lacked an understanding of the basic genetic makeup of the organism and the tools to differentiate the bacterium from other closely related species," said principal investigator Vivek Kapur, Ph.D., a faculty member in the University of Minnesota Medical School and College of Veterinary Medicine, director of the universitys Advanced Genetic Analysis Center and co-director of the Biomedical Genomics Center. "The genome sequence sheds new light on the genes and biochemical pathways in the bacterium, and the research offers a starting point for defining the mechanisms by which the organism causes disease and helping devise new strategies to detect infected animals and ultimately help control the spread of the organism."
M. paratuberculosis is a slow-growing bacterium that causes a chronic gastrointestinal infection in dairy cattle and other small ruminant species (such as sheep, goat, and deer) and has both serious health and economic consequences to dairy farming worldwide. While the bacterium has been recognized to cause Johnes disease for more than 100 years, methods for satisfactory diagnosis, treatment and prevention are lacking.
Deane Morrison | EurekAlert!
Carefully crafted light pulses control neuron activity
20.11.2017 | University of Illinois at Urbana-Champaign
Could this protein protect people against coronary artery disease?
17.11.2017 | University of North Carolina Health Care
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
20.11.2017 | Earth Sciences
20.11.2017 | Physics and Astronomy
17.11.2017 | Physics and Astronomy