The c-myc gene is commonly activated in a variety of human tumors. As a new report in the October 1 issue of Genes & Development shows, scientists are gaining a better understanding as to why.
Dr. John Cleveland and colleagues at St. Jude Childrens Research Hospital have discovered that c-Myc is essential for tumor development, as it regulates factors necessary for the growth of blood vessels into tumors – lending a new potential target to anti-angiogenic cancer therapies.
The myc family of oncogenes (c-myc, N-myc, and L-myc) function in the control of cell proliferation, differentiation, and tumorigenesis. Although it has long been recognized that c-Mycs positive effect on cell proliferation can contribute to cancer development, scientists have also suspected that c-Myc has additional roles in the progression of malignancy. Dr. Cleveland and colleagues have discovered such a role: c-Myc is essential for tumor angiogenesis.
Heather Cosel | EurekAlert!
Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard
New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
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